Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | TYMS | P04818 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8000218 | 0.93 | MEN1 (0.42) | MEN1KMT2ATYMSHTTSMN1; SMN2 | |
| SCHEMBL7998961 | 0.91 | NR1H4 (0.42) | MEN1KMT2A | |
| SCHEMBL8001066 | 0.91 | NR1H4 (0.42) | MEN1KMT2ATYMS | |
| SCHEMBL8001377 | 0.91 | MAPT (0.44) | MEN1KMT2ATYMS | |
| SCHEMBL8001670 | 0.89 | MEN1 (0.53) | MEN1KMT2ATYMSHTTSMN1; SMN2 | |
| SCHEMBL8002281 | 0.89 | MEN1 (0.53) | MEN1KMT2ATYMSHTTSMN1; SMN2 | |
| SCHEMBL7997374 | 0.87 | MEN1 (0.38) | MEN1KMT2ATYMSHTTPOLB | |
| SCHEMBL7997373 | 0.87 | MEN1 (0.38) | MEN1KMT2ATYMSHTT | |
| SCHEMBL8002143 | 0.86 | KDM4E (0.44) | MEN1KMT2AHTTSMN1; SMN2POLB | |
| SCHEMBL7998875 | 0.85 | MEN1 (0.49) | MEN1KMT2ATYMSHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |