SCHEMBL8080920

SCHEMBL8080920

OCC(O)COCC(COCC(COCC(O)CO)OCC(O)CO)OCC(O)CO

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.47
LMNA P02545 4/20 0.38
ALDH1A1 P00352 1/20 0.38
KDM4E B2RXH2 3/20 0.33
DUSP3 P51452 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
THRB P10828 1/20 0.32
CYP1A2 P05177 2/20 0.31
AGTR1 P30556 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6753202 1.00 USP2 (0.47) USP2LMNAALDH1A1KDM4EDUSP3
SCHEMBL19624530 0.98 USP2 (0.45) USP2LMNAALDH1A1KDM4EDUSP3
SCHEMBL13024094 0.98 USP2 (0.45) USP2LMNAALDH1A1KDM4EDUSP3
SCHEMBL6024951 0.98 USP2 (0.45) USP2LMNAALDH1A1KDM4EDUSP3
SCHEMBL10453102 0.95 USP2 (0.44) USP2LMNAALDH1A1KDM4EDUSP3
SCHEMBL12654048 0.95 USP2 (0.44) USP2LMNAALDH1A1KDM4EDUSP3
SCHEMBL17717979 0.93 USP2 (0.42) USP2LMNAALDH1A1KDM4EDUSP3
SCHEMBL3334101 0.93 USP2 (0.45) USP2LMNAALDH1A1KDM4EDUSP3
SCHEMBL24844033 0.91 USP2 (0.41) USP2LMNAALDH1A1KDM4EDUSP3
SCHEMBL18117580 0.91 USP2 (0.41) USP2LMNAALDH1A1KDM4EDUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2997037-A2 COMPOSITION AND METHODS FOR ENTRAPPING A PROTEIN ON A SURFACE Genomics Usa, Inc. (US) 2016-03-23 EP disclosed
WO-2014185960-A9 COMPOSITION AND METHODS FOR ENTRAPPING A PROTEIN ON A SURFACE GENOMICS USA, INC. (US) 2015-03-05 WO disclosed
WO-2014185960-A2 COMPOSITION AND METHODS FOR ENTRAPPING A PROTEIN ON A SURFACE GENOMICS USA, INC. (US) 2014-11-20 WO disclosed
US-6074683-A REACTING A 2-HYDROXYALKYL-SUBSTITUTED 4-HYDROXY-3(2H)-FURANONE WITH H2S AND/OR CYSTEINE LIPTON, INC. (US) 2000-06-13 US disclosed
US-4353958-A POLYURETHANE BINDER NARUMI CHINA CORPORATION (JP) 1982-10-12 US disclosed