SCHEMBL8081633

SCHEMBL8081633

CCCCCCCCCC(=O)Oc1ccc(C(=O)Cl)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
ESR1 P03372 3/20 0.50
MEN1 O00255 1/20 0.49
SLC22A2 O15244 1/20 0.49
TMPRSS2 O15393 1/20 0.49
F2 P00734 1/20 0.49
F10 P00742 1/20 0.49
PLG P00747 1/20 0.49
F12 P00748 1/20 0.49
PLAU P00749 1/20 0.49
PLAT P00750 1/20 0.49
KLKB1 P03952 1/20 0.49
CYP1A2 P05177 1/20 0.49
HPN P05981 1/20 0.49
CHRM2 P08172 1/20 0.49
CYP2D6 P10635 1/20 0.49
SLC6A2 P23975 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11233043 1.00 KMT2A (0.57) KMT2ASMN1; SMN2NPC1RAB9AESR1
SCHEMBL8861904 1.00 KMT2A (0.57) KMT2ASMN1; SMN2NPC1RAB9AESR1
SCHEMBL9816516 1.00 KMT2A (0.57) KMT2ASMN1; SMN2NPC1RAB9AESR1
SCHEMBL10349269 1.00 KMT2A (0.57) KMT2ASMN1; SMN2NPC1RAB9AESR1
SCHEMBL11115353 0.98 KMT2A (0.55) KMT2ASMN1; SMN2NPC1RAB9AESR1
SCHEMBL8377371 0.96 KMT2A (0.53) KMT2ASMN1; SMN2NPC1RAB9AESR1
SCHEMBL9329652 0.96 KMT2A (0.53) KMT2ASMN1; SMN2NPC1RAB9AESR1
SCHEMBL9124628 0.94 KMT2A (0.52) KMT2ASMN1; SMN2NPC1RAB9AESR1
SCHEMBL8861896 0.94 KMT2A (0.52) KMT2ASMN1; SMN2NPC1RAB9AESR1
SCHEMBL5696854 0.88 KMT2A (0.68) KMT2ASMN1; SMN2NPC1RAB9AESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0780456-B1 Anti-ferroelectric liquid crystal compound and anti-ferroelectric liquid crystal composition MITSUBISHI GAS CHEMICAL CO (JP) 2000-10-11 EP disclosed
US-5723069-A Anti-ferroelectric liquid crystal compound and anti-ferroelectric liquid crystal composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1998-03-03 US disclosed
EP-0780456-A1 Anti-ferroelectric liquid crystal compound and anti-ferroelectric liquid crystal composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1997-06-25 EP disclosed
EP-0586263-B1 A liquid crystal compound SHOWA SHELL SEKIYU (JP) 1997-03-26 EP disclosed
US-5433887-A Liquid crystal compounds SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1995-07-18 US disclosed
EP-0468882-B1 Liquid crystal compound SHOWA SHELL SEKIYU (JP) 1995-02-22 EP disclosed
US-5330678-A HAVING AN EXCELLENT LIGHT LEAKING RATIO UNDER TRISTABLE STATES SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1994-07-19 US disclosed
EP-0586263-A1 A liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1994-03-09 EP disclosed
EP-0468882-A1 Liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1992-01-29 EP disclosed