SCHEMBL8081880 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	HTR2C	P28335	2/20	0.32

▸	SLC6A4	P31645	2/20	0.32

▸	CCNE2	O96020	1/20	0.32

▸	CCNE1	P24864	1/20	0.32

▸	CDK2	P24941	1/20	0.32

▸	PDK2	Q15119	1/20	0.31

▸	LMNA	P02545	1/20	0.30

▸	MAPT	P10636	1/20	0.30

▸	HTT	P42858	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL499983	0.86	HTR2C (0.35)	HTR2CSLC6A4CCNE2CCNE1CDK2
SCHEMBL10254301	0.85	HTR2C (0.33)	HTR2CSLC6A4CCNE2CCNE1CDK2
SCHEMBL499753	0.85	HTR2C (0.33)	HTR2CSLC6A4CCNE2CCNE1CDK2
SCHEMBL499754	0.85	HTR2C (0.33)	HTR2CSLC6A4CCNE2CCNE1CDK2
SCHEMBL499755	0.85	HTR2C (0.33)	HTR2CSLC6A4CCNE2CCNE1CDK2
SCHEMBL499316	0.77	HTR2C (0.33)	HTR2CSLC6A4PDK2LMNAMAPT
SCHEMBL499315	0.77	HTR2C (0.33)	HTR2CSLC6A4PDK2LMNAMAPT
SCHEMBL10254273	0.77	HTR2C (0.33)	HTR2CSLC6A4PDK2LMNAMAPT
SCHEMBL499317	0.77	HTR2C (0.33)	HTR2CSLC6A4PDK2LMNAMAPT
SCHEMBL499010	0.77	PDK2 (0.35)	HTR2CSLC6A4PDK2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2008156816-A2	RENIN INHIBITORS	VITAE PHARMACEUTICALS, INC. (US)	2008-12-24	—	—	WO	disclosed