Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.42 |
| ▸ | FDPS | P14324 | 9/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31338939 | 1.00 | TSHR (0.50) | TSHRTHRBCES2LPAR1LPAR3 | |
| SCHEMBL27977478 | 1.00 | TSHR (0.50) | TSHRTHRBCES2LPAR1LPAR3 | |
| SCHEMBL27977800 | 0.97 | TSHR (0.47) | TSHRTHRBCES2LPAR1LPAR3 | |
| SCHEMBL1116286 | 0.97 | TSHR (0.47) | TSHRTHRBCES2LPAR1LPAR3 | |
| SCHEMBL1116252 | 0.97 | TSHR (0.47) | TSHRTHRBCES2LPAR1LPAR3 | |
| SCHEMBL1115970 | 0.97 | TSHR (0.47) | TSHRTHRBCES2LPAR1LPAR3 | |
| SCHEMBL1116251 | 0.94 | TSHR (0.50) | TSHRTHRBCES2LPAR1LPAR3 | |
| SCHEMBL1116260 | 0.94 | TSHR (0.50) | TSHRTHRBCES2LPAR1LPAR3 | |
| SCHEMBL1116250 | 0.94 | TSHR (0.50) | TSHRTHRBCES2LPAR1LPAR3 | |
| SCHEMBL21925326 | 0.94 | TSHR (0.50) | TSHRTHRBCES2LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025031-A | ACRYLATE COPOLYMER, POLYESTER AND POLYURETHANE RESIN MIXTURES WITH CROSSLINKING AGENTS | BASF COATINGS AG (DE) | 2000-02-15 | — | — | US | disclosed |