Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.43 |
| ▸ | VEGFA | P15692 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.35 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081702 | 0.80 | TLR8 (0.44) | TSHREPAS1TDP1ALDH1A1HPGD | |
| SCHEMBL10979888 | 0.79 | TDP1 (0.50) | TSHRTDP1ALDH1A1HPGDCYP3A4 | |
| SCHEMBL28302342 | 0.78 | EPAS1 (0.39) | TSHREPAS1VEGFATDP1ALDH1A1 | |
| SCHEMBL11333931 | 0.75 | TSHR (0.46) | TSHREPAS1VEGFATDP1ALDH1A1 | |
| SCHEMBL10708527 | 0.74 | NOTUM (0.36) | CYP3A4GRIN2BNOTUMGRIA1CACNG8 | |
| SCHEMBL9350046 | 0.74 | TSHR (0.48) | TSHREPAS1VEGFATDP1ALDH1A1 | |
| SCHEMBL10980919 | 0.73 | TSHR (0.62) | TSHRTDP1ALDH1A1HSD17B10GRIN2D | |
| SCHEMBL7686888 | 0.73 | HSD17B10 (0.55) | ALDH1A1HPGDCYP3A4HSD17B10MEN1 | |
| SCHEMBL11047126 | 0.72 | TDP1 (0.56) | TSHREPAS1VEGFATDP1ALDH1A1 | |
| SCHEMBL16175252 | 0.71 | TSHR (0.41) | TSHREPAS1VEGFATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820981-B1 | Process for the preparation of 2-trifluoromethoxy-aniline | BAYER AG (DE) | 2000-10-18 | — | — | EP | claimed |
| US-5840983-A | Process for preparing 2-trifluoromethoxy-aniline | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-24 | — | — | US | claimed |
| EP-0820981-A1 | Process for the preparation of 2-trifluoromethoxy-aniline | BAYER AG (DE) | 1998-01-28 | — | — | EP | claimed |
| EP-0820981-B1 | Process for the preparation of 2-trifluoromethoxy-aniline | BAYER AG (DE) | 2000-10-18 | — | — | EP | disclosed |
| US-5840983-A | Process for preparing 2-trifluoromethoxy-aniline | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-24 | — | — | US | disclosed |
| US-5840983-A | Process for preparing 2-trifluoromethoxy-aniline | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-24 | — | — | US | disclosed |
| EP-0820981-A1 | Process for the preparation of 2-trifluoromethoxy-aniline | BAYER AG (DE) | 1998-01-28 | — | — | EP | disclosed |
| EP-0820981-A1 | Process for the preparation of 2-trifluoromethoxy-aniline | BAYER AG (DE) | 1998-01-28 | — | — | EP | disclosed |