Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CCL2 | P13500 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651586 | 0.80 | HTR2A (0.40) | HTR2AHTR6SIGMAR1BRD4CCL2 | |
| Lithium SCHEMBL9142074 | 0.78 | HTR2A (0.39) | HTR2AHTR6SIGMAR1BRD4CCL2 | |
| SCHEMBL9142060 | 0.78 | HTR2A (0.39) | HTR2AHTR6SIGMAR1BRD4CCL2 | |
| SCHEMBL9144853 | 0.78 | HTR2A (0.39) | HTR2AHTR6SIGMAR1BRD4CCL2 | |
| SCHEMBL8668908 | 0.78 | HTR2A (0.39) | HTR2AHTR6SIGMAR1BRD4CCL2 | |
| SCHEMBL9144861 | 0.78 | HTR2A (0.39) | HTR2AHTR6SIGMAR1BRD4CCL2 | |
| SCHEMBL3404077 | 0.77 | HTR2A (0.38) | HTR2AHTR6SIGMAR1BRD4CCL2 | |
| SCHEMBL4652559 | 0.77 | HTR2A (0.38) | HTR2AHTR6SIGMAR1BRD4CCL2 | |
| Lithium SCHEMBL8578281 | 0.75 | HTR2A (0.36) | HTR2AHTR6SIGMAR1BRD4CCL2 | |
| SCHEMBL9148580 | 0.75 | HTR2A (0.36) | HTR2AHTR6SIGMAR1BRD4CCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376154-B2 | Bisindenyl derivative and method for its preparation | TARGOR GMBH (DE) | 2000-09-27 | — | — | EP | disclosed |
| EP-0679662-B1 | Catalyst component for the polymerization of olefins | NIPPON OIL CO LTD (JP) | 1999-07-14 | — | — | EP | disclosed |
| EP-0569249-B1 | Ethylene/alpha-olefin copolymers | NIPPON OIL CO LTD (JP) | 1997-08-06 | — | — | EP | disclosed |
| EP-0692486-A2 | Bisindenyl derivative and process for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-17 | — | — | EP | disclosed |
| EP-0679662-A1 | Catalyst component for the polymerization of olefins | NIPPON OIL CO. LTD. (JP) | 1995-11-02 | — | — | EP | disclosed |
| EP-0569249-A2 | Ethylene/alpha-olefin copolymers | NIPPON OIL COMPANY, LIMITED (JP) | 1993-11-10 | — | — | EP | disclosed |
| US-4985576-A | Bisindenyl derivative, and a process for the preparation thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-15 | — | — | US | disclosed |
| EP-0376154-A2 | Bisindenyl derivative and method for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-07-04 | — | — | EP | disclosed |