SCHEMBL808391

SCHEMBL808391

BrC1C=Cc2[nH]c3ccccc3c2C1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
NR2E1 Q9Y466 2/20 0.40
HSD17B10 Q99714 2/20 0.38
ALDH1A1 P00352 1/20 0.38
GPR3 P46089 1/20 0.38
ADRA1D P25100 1/20 0.37
ADRA1A P35348 1/20 0.37
ADRA1B P35368 1/20 0.37
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
BRD3 Q15059 1/20 0.36
KDM4E B2RXH2 1/20 0.36
HTR5A P47898 1/20 0.36
NISCH Q9Y2I1 1/20 0.36
HTR7 P34969 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089401 0.80 MEN1 (0.49) MEN1KMT2ANR2E1HSD17B10ADRA1D
SCHEMBL1755392 0.79 CDK4 (0.33) HSD17B10ALDH1A1HTR2AHTR2CKDM4E
SCHEMBL12967517 0.76
SCHEMBL26346100 0.72 HPGD (0.44) MEN1KMT2ANR2E1ADRA1DADRA1A
SCHEMBL15925514 0.71 MEN1 (0.47) MEN1KMT2ANR2E1HSD17B10ALDH1A1
SCHEMBL5891207 0.69 HSD17B10 (0.44) MEN1KMT2ANR2E1HSD17B10ALDH1A1
SCHEMBL16773851 0.69 KMT2A (0.36) MEN1KMT2AHSD17B10ALDH1A1KDM4E
SCHEMBL20616992 0.68 MEN1 (0.38) MEN1KMT2ANR2E1HSD17B10ALDH1A1
SCHEMBL24684633 0.68 MEN1 (0.35) MEN1KMT2ANR2E1HSD17B10ALDH1A1
SCHEMBL24863103 0.67 MEN1 (0.34) MEN1KMT2ANR2E1HSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3219704-A1 ORGANIC MOLECULES FOR USE AS EMITTERS cynora GmbH (DE) 2017-09-20 EP disclosed
WO-2012036482-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2012-03-22 WO disclosed