Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.85 |
| ▸ | ITGB3 | P05106 | 17/20 | 0.85 |
| ▸ | ITGB6 | P18564 | 7/20 | 0.70 |
| ▸ | ITGB8 | P26012 | 4/20 | 0.70 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.68 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.63 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.62 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084082 | 1.00 | ITGAV (0.85) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL8085838 | 1.00 | ITGAV (0.85) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL6421095 | 0.92 | ITGAV (1.00) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL6358670 | 0.92 | ITGAV (1.00) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL6421090 | 0.92 | ITGAV (1.00) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL8085557 | 0.90 | ITGAV (1.00) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL8084105 | 0.90 | ITGAV (1.00) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL8079600 | 0.90 | ITGAV (1.00) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL7437065 | 0.88 | ITGAV (0.84) | ITGAVITGB3ITGB6ITGB8ITGA2B | |
| SCHEMBL7444216 | 0.88 | ITGAV (0.84) | ITGAVITGB3ITGB6ITGB8ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048861-A | OSTEOPOROSIS; BONE DISORDERS; CARDIOVASCULAR DISORDERS; ANTIINFLAMMATROY AGENTS; WOUND HEALING AGENTS | MERCK & CO., INC. (US) | 2000-04-11 | — | — | US | claimed |