Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530023 | 1.00 | TSHR (0.38) | TSHRGABRR1GABRR2BLMLMNA | |
| SCHEMBL8084257 | 1.00 | TSHR (0.38) | TSHRGABRR1GABRR2BLMLMNA | |
| SCHEMBL585109 | 0.84 | TSHR (0.50) | TSHRGABRR1GABRR2BLMLMNA | |
| SCHEMBL585108 | 0.84 | TSHR (0.50) | TSHRGABRR1GABRR2BLMLMNA | |
| SCHEMBL8533019 | 0.78 | CNR2 (0.38) | TSHRGABRR1GABRR2BLMLMNA | |
| SCHEMBL8091033 | 0.78 | CNR2 (0.38) | TSHRGABRR1GABRR2BLMLMNA | |
| SCHEMBL8091035 | 0.78 | CNR2 (0.38) | TSHRGABRR1GABRR2BLMLMNA | |
| SCHEMBL12594514 | 0.77 | ABCC4 (0.34) | — | |
| SCHEMBL8206235 | 0.74 | MAPT (0.47) | LMNANPSR1TP53 | |
| SCHEMBL4344531 | 0.72 | PTPN1 (0.43) | TSHRGABRR1GABRR2BLMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6018054-A | INTERMEDIATE COMPOUNDS FOR PREPARING NOVEL QUINOLONE AND NAPHTHYRIDONE DERIVATIVES WHICH ARE SUBSTITUTED IN THE 7-POSITION BY A PARTIALLY HYDROGENATED ISOINDOLINYL RING, USE AS ANTIBACTERIAL AGENTS AND AS FEED ADDITIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-01-25 | — | — | US | disclosed |
| US-5556979-A | ANIMAL FEEDS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-17 | — | — | US | disclosed |
| US-5508278-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-16 | — | — | US | disclosed |