SCHEMBL8084559

SCHEMBL8084559

COc1ccc(-n2nc(C(=O)NO)c3c2C(=O)N(c2ccc(N4CCCCC4=O)cc2)CC3)cc1

nearest known ligand 0.79

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.79
F2 P00734 5/20 0.79
SLC29A1 Q99808 1/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22478593 0.92 F10 (0.81) F10F2SLC29A1
SCHEMBL18744310 0.91 F10 (0.77) F10F2SLC29A1
SCHEMBL15883174 0.90 F10 (0.82) F10F2SLC29A1
SCHEMBL18365276 0.90 F10 (0.85) F10F2SLC29A1
SCHEMBL24168568 0.90 F10 (0.75) F10F2SLC29A1
SCHEMBL5445803 0.89 F10 (0.84) F10F2SLC29A1
SCHEMBL28365263 0.89 F10 (0.82) F10F2SLC29A1
SCHEMBL17507083 0.89 F10 (0.82) F10F2SLC29A1
SCHEMBL23777828 0.89 F10 (0.82) F10F2SLC29A1
Apixaban SCHEMBL118023 0.89 F10 (1.00) F10F2SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118724753-A Method for promoting synthesis of hydroxamic acid by using metal salt 沈阳药科大学 2024-10-01 CN disclosed
CN-107400131-B Apixaban derivatives, preparation method and application thereof 沈阳药科大学 2021-03-12 CN disclosed
WO-2009018807-A9 OXAZOLIDINONES AS FACTOR XA INHIBITORS, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF IN THERAPY SCHEBO BIOTECH AG (DE) 2009-11-12 WO disclosed
WO-2009018807-A1 NOVEL PHARMACEUTICALS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF IN THERAPY SCHEBO BIOTECH AG (DE) 2009-02-12 WO disclosed