SCHEMBL8084575

SCHEMBL8084575

CCCCCCCCCCCCCCC(=O)Cc1ccc(-c2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
ABCC4 O15439 1/20 0.53
LMNA P02545 1/20 0.53
GAA P10253 1/20 0.53
TSHR P16473 1/20 0.53
PTGS1 P23219 1/20 0.53
HTT P42858 1/20 0.53
POLB P06746 1/20 0.51
RARB P10826 5/20 0.50
ALDH1A1 P00352 1/20 0.50
RARA P10276 1/20 0.50
MAPT P10636 1/20 0.50
MTOR P42345 1/20 0.50
EPHX2 P34913 1/20 0.49
CES2 O00748 1/20 0.49
CES1 P23141 1/20 0.49
SOAT1 P35610 2/20 0.48
HDAC1 Q13547 1/20 0.48
HDAC2 Q92769 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28089503 0.90 KMT2A (0.66) MEN1KMT2AALDH1A1MAPTEPHX2
SCHEMBL28382194 0.90 KMT2A (0.66) MEN1KMT2AALDH1A1MAPTEPHX2
SCHEMBL26445070 0.90 KMT2A (0.66) MEN1KMT2AALDH1A1MAPTEPHX2
SCHEMBL547836 0.90 KMT2A (0.66) MEN1KMT2AALDH1A1MAPTEPHX2
SCHEMBL9060468 0.90 KMT2A (0.66) MEN1KMT2AALDH1A1MAPTEPHX2
SCHEMBL7034273 0.90 KMT2A (0.66) MEN1KMT2AALDH1A1MAPTEPHX2
SCHEMBL7038549 0.90 KMT2A (0.66) MEN1KMT2AALDH1A1MAPTEPHX2
SCHEMBL7036521 0.90 KMT2A (0.66) MEN1KMT2AALDH1A1MAPTEPHX2
SCHEMBL8084828 0.90 KMT2A (0.66) MEN1KMT2AALDH1A1MAPTEPHX2
SCHEMBL8510522 0.90 KMT2A (0.66) MEN1KMT2AALDH1A1MAPTEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6165234-A FOR IMPARTING REVERSIBLE COLOR CHANGES TO WAXES AND CANDLES WHEN HEATED OR WHEN WAX MELTS OR WHEN THE CANDLE BURNS KANAKKANATT SEBASTIAN V (US) 2000-12-26 US disclosed