Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.53 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27954310 | 1.00 | HTT (0.58) | HTTMEN1KMT2AFFAR1PLA2G2A | |
| SCHEMBL10596742 | 1.00 | HTT (0.58) | HTTMEN1KMT2AFFAR1PLA2G2A | |
| SCHEMBL27954307 | 1.00 | HTT (0.58) | HTTMEN1KMT2AFFAR1PLA2G2A | |
| SCHEMBL27944650 | 1.00 | HTT (0.58) | HTTMEN1KMT2AFFAR1PLA2G2A | |
| SCHEMBL27954283 | 1.00 | HTT (0.58) | HTTMEN1KMT2AFFAR1PLA2G2A | |
| SCHEMBL9768518 | 1.00 | HTT (0.58) | HTTMEN1KMT2AFFAR1PLA2G2A | |
| SCHEMBL8712689 | 0.93 | CSNK2A1 (0.55) | HTTMEN1KMT2AFFAR1PLA2G2A | |
| SCHEMBL10786547 | 0.93 | CSNK2A1 (0.58) | HTTMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8674913 | 0.87 | HTT (0.71) | HTTMEN1KMT2AFFAR1PLA2G2A | |
| SCHEMBL11074148 | 0.86 | HPGD (0.61) | HTTMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |