Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | ACHE | P22303 | 4/20 | 0.67 |
| ▸ | SNCA | P37840 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | CNR2 | P34972 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA3 | P07451 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085985 | 1.00 | KDM4E (0.76) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL7966717 | 0.99 | KDM4E (0.74) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL7966711 | 0.99 | KDM4E (0.74) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL2282651 | 0.95 | KDM4E (0.85) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL2282643 | 0.95 | KDM4E (0.85) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL7966395 | 0.94 | KDM4E (0.83) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL7966392 | 0.94 | KDM4E (0.83) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL13168884 | 0.93 | KDM4E (0.75) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL13168883 | 0.93 | KDM4E (0.75) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL11231174 | 0.92 | KDM4E (0.90) | KDM4EALDH1A1HPGDALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |