Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATF4 | P18848 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009654 | 0.85 | GRIN1 (0.49) | GRIN1GRIN2BMAPTHTTKCNH2 | |
| SCHEMBL12576447 | 0.84 | GRIN1 (0.51) | GRIN1GRIN2BMAPTHTTKCNH2 | |
| SCHEMBL2016246 | 0.84 | GRIN1 (0.72) | GRIN1GRIN2BKCNH2 | |
| SCHEMBL2016248 | 0.84 | GRIN1 (0.72) | GRIN1GRIN2BKCNH2 | |
| SCHEMBL14864160 | 0.75 | GRIN1 (0.54) | GRIN1GRIN2BMAPTHTTKCNH2 | |
| SCHEMBL12576482 | 0.74 | MAPT (0.68) | MAPTHTTKCNH2LMNASMN1; SMN2 | |
| SCHEMBL2023658 | 0.74 | KCNH2 (0.68) | MAPTHTTKCNH2CACNA1GLMNA | |
| SCHEMBL2023657 | 0.74 | KCNH2 (0.68) | MAPTHTTKCNH2CACNA1GLMNA | |
| SCHEMBL2025770 | 0.74 | KCNH2 (0.61) | MAPTKCNH2DRD2DRD3CACNA1G | |
| SCHEMBL2025768 | 0.74 | KCNH2 (0.61) | MAPTKCNH2DRD2DRD3CACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009006437-A1 | NMDA RECEPTOR ANTAGONISTS FOR NEUROPROTECTION | EMORY UNIVERSITY (US) | 2009-01-08 | — | — | WO | disclosed |