Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20349607 | 0.86 | KMT2A (1.00) | KMT2AMEN1CNR1CYP1A2CYP3A4 | |
| SCHEMBL9563917 | 0.85 | KMT2A (0.97) | KMT2AMEN1CNR1CYP1A2CYP3A4 | |
| SCHEMBL18724726 | 0.83 | MEN1 (0.78) | KMT2AMEN1CNR1CYP1A2CYP3A4 | |
| SCHEMBL10576190 | 0.83 | MEN1 (0.78) | KMT2AMEN1CNR1CYP1A2CYP3A4 | |
| SCHEMBL19745509 | 0.82 | KMT2A (0.76) | KMT2AMEN1CNR1CYP1A2CYP3A4 | |
| SCHEMBL19204683 | 0.82 | MEN1 (0.76) | KMT2AMEN1CNR1CYP1A2CYP3A4 | |
| SCHEMBL11741945 | 0.81 | MEN1 (0.66) | KMT2AMEN1CNR1CYP1A2CYP3A4 | |
| SCHEMBL10589645 | 0.80 | KMT2A (0.72) | KMT2AMEN1CNR1EPHX2ALDH1A1 | |
| SCHEMBL4377309 | 0.78 | HRH3 (0.74) | KMT2AMEN1CNR1CYP1A2CYP3A4 | |
| SCHEMBL16002963 | 0.78 | MEN1 (0.69) | KMT2AMEN1CNR1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008150447-A1 | AMIDE COMPOUNDS AND THE USE THEREOF | EURO-CELTIQUE S.A. (LU) | 2008-12-11 | — | — | WO | disclosed |