Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.41 |
| ▸ | KDM1A | O60341 | 7/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13045326 | 0.86 | DPP4 (0.56) | DPP4 | |
| SCHEMBL8092647 | 0.85 | DPP4 (0.51) | DPP4KDM1AMGLL | |
| SCHEMBL13045331 | 0.85 | DPP4 (0.51) | DPP4KDM1AMGLL | |
| Trifluoroacetic Acid SCHEMBL3742822 | 0.82 | DPP4 (0.55) | DPP4 | |
| Trifluoroacetic Acid SCHEMBL3742854 | 0.82 | DPP4 (0.55) | DPP4 | |
| Trifluoroacetic Acid SCHEMBL3745725 | 0.82 | DPP4 (0.55) | DPP4 | |
| Trifluoroacetic Acid SCHEMBL3740209 | 0.82 | DPP4 (0.55) | DPP4 | |
| Trifluoroacetic Acid SCHEMBL3741051 | 0.80 | DPP4 (0.46) | DPP4KDM1AMGLL | |
| Trifluoroacetic Acid SCHEMBL3742559 | 0.79 | DPP4 (0.45) | DPP4 | |
| SCHEMBL14300764 | 0.77 | DPP4 (0.38) | DPP4KDM1AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037719-A1 | NOVEL COMPOUNDS AS DIPEPTIDYL PEPTIDASE IV (DPP IV) INHIBITORS | LUPIN LIMITED (IN) | 2009-03-26 | — | — | WO | disclosed |