Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095659 | 0.98 | SKP2 (0.46) | SKP2MAOBESR1ESR2ALDH1A1 | |
| SCHEMBL8096326 | 0.98 | SKP2 (0.46) | SKP2MAOBESR1ESR2ALDH1A1 | |
| SCHEMBL8095641 | 0.98 | SKP2 (0.46) | SKP2MAOBESR1ESR2ALDH1A1 | |
| SCHEMBL8086465 | 0.98 | SKP2 (0.46) | SKP2MAOBESR1ESR2ALDH1A1 | |
| SCHEMBL8099059 | 0.98 | SKP2 (0.46) | SKP2MAOBESR1ESR2ALDH1A1 | |
| SCHEMBL8094859 | 0.98 | SKP2 (0.46) | SKP2MAOBESR1ESR2ALDH1A1 | |
| SCHEMBL8101489 | 0.98 | SKP2 (0.46) | SKP2MAOBESR1ESR2ALDH1A1 | |
| SCHEMBL8100282 | 0.98 | SKP2 (0.46) | SKP2MAOBESR1ESR2ALDH1A1 | |
| SCHEMBL8094499 | 0.98 | SKP2 (0.46) | SKP2MAOBESR1ESR2ALDH1A1 | |
| SCHEMBL8094887 | 0.98 | SKP2 (0.46) | SKP2MAOBESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |