Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 5/20 | 0.54 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.54 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.52 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.52 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GSR | P00390 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL8087513 | 1.00 | GRIK1 (0.54) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL18278900 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL6272135 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL28770688 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL1076156 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL23322528 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL8205527 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL1938072 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL21994940 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL28354172 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109924342-A | A kind of mixed feed and feed addictive and preparation method thereof for reducing sow and limb hoof disease occurring | 广东广垦畜牧工程研究院有限公司 | 2019-06-25 | — | — | CN | claimed |
| CN-107397156-A | A kind of octopus section boiling method | 舟山市齐晟水产有限公司 | 2017-11-28 | — | — | CN | claimed |
| CN-106858081-A | A kind of beef cattle special feed and preparation method | 南宁学院 | 2017-06-20 | — | — | CN | claimed |
| CN-106359488-A | Rooting agent containing water lily extracting solution and preparation method thereof | 山东胜伟园林科技有限公司 | 2017-02-01 | — | — | CN | claimed |
| CN-106135909-A | A kind of food compositions and its production and use | 重庆两江药物研发中心有限公司 | 2016-11-23 | — | — | CN | claimed |
| CN-105941890-A | Concentrate supplementing feed for preventing yellow fat of fattening sheep | 甘肃农业大学 | 2016-09-21 | — | — | CN | claimed |
| CN-104262187-A | Method for solid-phase synthesis of magnesium aspartate at room temperature | CHINA NAT RES INST OF FOOD AND FERMENTATION IND | 2015-01-07 | — | — | CN | claimed |
| CN-104262186-A | Method for low-temperature solid phase synthesis of magnesium L-aspartate | CHINA NAT RES INST OF FOOD AND FERMENTATION IND | 2015-01-07 | — | — | CN | claimed |
| CN-102228676-B | Heparolysate injection pharmaceutical composition | Bethune Medical University Pharmaceutical Factory | 2013-01-30 | — | — | CN | claimed |
| CN-102875402-A | Method for preparing magnesium L-aspartate | YIXING QIANCHENG BIOLOG CO LTD | 2013-01-16 | — | — | CN | claimed |
| CN-102228676-A | Heparolysate injection pharmaceutical composition | Bethune Medical University Pharmaceutical Factory | 2011-11-02 | — | — | CN | claimed |
| CN-100551900-C | A kind of preparation method of aspartic acid | YONG ZHANG (CN) | 2009-10-21 | — | — | CN | claimed |
| CN-100551901-C | A kind of preparation method of Magnesium Aspartate | YONG ZHANG (CN) | 2009-10-21 | — | — | CN | claimed |
| CN-100427413-C | Trielement synergistic corrosion inhibitor | BEIJING UNIV OF CHEMISTRY (CN) | 2008-10-22 | — | — | CN | claimed |
| CN-101239925-A | Method for preparing magnesium aspartate | BEIJING JINGWEI XINKANG PHARMA (CN) | 2008-08-13 | — | — | CN | claimed |
| CN-101234992-A | Method for preparing aspartic acid | BEIJING JINGWEI XINGKANG PHARM (CN) | 2008-08-06 | — | — | CN | claimed |
| CN-1868924-A | Trielement synergistic corrosion inhibitor | BEIJING UNIV OF CHEMISTRY (CN) | 2006-11-29 | — | — | CN | claimed |
| CN-1197623-C | Sparagin injection using xylitol as isosmotic adjusting agent | SIHEYOU MEDICAL SCI & TECH CO (CN) | 2005-04-20 | — | — | CN | claimed |
| CN-1548076-A | Liquid composition prepn of magnesium salt and blood circulation promoting and blood clots dispersing Chinese medicine | 张 航 | 2004-11-24 | — | — | CN | claimed |
| CN-1451438-A | Sparagin injection using xylitol as isosmotic adjusting agent | SIHEYOU MEDICAL SCI & TECH CO (CN) | 2003-10-29 | — | — | CN | claimed |