Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086530 | 1.00 | HTR2A (0.46) | HTR2ACYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL8098331 | 1.00 | HTR2A (0.46) | HTR2ACYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL8096307 | 1.00 | HTR2A (0.46) | HTR2ACYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL8095644 | 1.00 | HTR2A (0.46) | HTR2ACYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL8093111 | 1.00 | HTR2A (0.46) | HTR2ACYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL8086302 | 1.00 | HTR2A (0.46) | HTR2ACYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL8094072 | 1.00 | HTR2A (0.46) | HTR2ACYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL8095550 | 1.00 | HTR2A (0.46) | HTR2ACYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL8093330 | 1.00 | HTR2A (0.46) | HTR2ACYP3A4ALDH1A1TSHRTDP1 | |
| SCHEMBL8101442 | 1.00 | HTR2A (0.46) | HTR2ACYP3A4ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |