Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480758 | 0.86 | CA1 (0.50) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL8480763 | 0.86 | CA1 (0.50) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL3250286 | 0.86 | CA1 (0.50) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL11818262 | 0.84 | CES1 (0.47) | HDAC3HDAC1HDAC2CES2CES1 | |
| SCHEMBL10397714 | 0.82 | PTAFR (0.51) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL10397715 | 0.82 | PTAFR (0.51) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL9519833 | 0.78 | HDAC3 (0.49) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL9519828 | 0.78 | HDAC3 (0.49) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL9519824 | 0.78 | HDAC3 (0.49) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL10357853 | 0.76 | NQO2 (0.47) | HDAC3HDAC1HDAC2HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0862550-B1 | CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF AG (DE) | 2000-11-08 | — | — | EP | disclosed |
| EP-0862550-A1 | CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997009294-A1 | CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1997-03-13 | — | — | WO | disclosed |