Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 7/20 | 0.56 |
| ▸ | BCHE | P06276 | 2/20 | 0.56 |
| ▸ | TGM2 | P21980 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.50 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CDC25A | P30304 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4625229 | 0.83 | CES1 (0.61) | CES1BCHETGM2ALDH1A1AGTR1 | |
| SCHEMBL12930202 | 0.82 | CES1 (0.65) | CES1BCHETGM2ALDH1A1AGTR1 | |
| SCHEMBL25920080 | 0.82 | CES1 (0.65) | CES1BCHETGM2ALDH1A1AGTR1 | |
| SCHEMBL10679097 | 0.77 | CES1 (0.57) | CES1BCHETGM2ALDH1A1AGTR1 | |
| SCHEMBL12930273 | 0.76 | CES1 (0.61) | CES1BCHETGM2ALDH1A1AGTR1 | |
| SCHEMBL6142742 | 0.75 | CES1 (0.59) | CES1BCHETGM2ALDH1A1AGTR1 | |
| SCHEMBL6143112 | 0.75 | CES1 (0.51) | CES1BCHETGM2ALDH1A1AGTR1 | |
| SCHEMBL4624656 | 0.75 | CES1 (0.59) | CES1BCHETGM2ALDH1A1AGTR1 | |
| SCHEMBL1426402 | 0.73 | CES1 (0.71) | CES1BCHETGM2ALDH1A1ALDH3A1 | |
| SCHEMBL5114051 | 0.73 | CES1 (0.71) | CES1BCHETGM2ALDH1A1ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750490-B1 | ISATIN DERIVATIVES FOR DYEING KERATIN-CONTAINING FIBRES | HENKEL KGAA (DE) | 2000-11-08 | — | — | EP | claimed |
| EP-0750490-A1 | ISATIN DERIVATIVES FOR DYEING KERATIN-CONTAINING FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1997-01-02 | — | — | EP | claimed |
| WO-1995024886-A1 | ISATIN DERIVATIVES FOR DYEING KERATIN-CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1995-09-21 | — | — | WO | claimed |
| EP-0750490-B1 | ISATIN DERIVATIVES FOR DYEING KERATIN-CONTAINING FIBRES | HENKEL KGAA (DE) | 2000-11-08 | — | — | EP | disclosed |
| US-5743919-A | HAIR DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1998-04-28 | — | — | US | disclosed |
| EP-0750490-A1 | ISATIN DERIVATIVES FOR DYEING KERATIN-CONTAINING FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995024886-A1 | ISATIN DERIVATIVES FOR DYEING KERATIN-CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1995-09-21 | — | — | WO | disclosed |