Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 18/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.56 |
| ▸ | PGK1 | P00558 | 1/20 | 0.50 |
| ▸ | PGK2 | P07205 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208192 | 0.89 | ADORA2A (0.59) | ADORA2AADORA3ADORA2BADORA1PGK1 | |
| SCHEMBL7205271 | 0.86 | ADORA2A (0.59) | ADORA2AADORA3ADORA2BADORA1PGK1 | |
| SCHEMBL7206736 | 0.86 | ADORA2A (0.59) | ADORA2AADORA3ADORA2BADORA1PGK1 | |
| SCHEMBL7103921 | 0.86 | ADORA2A (0.60) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7099511 | 0.86 | ADORA2A (0.58) | ADORA2AADORA3ADORA2BADORA1PGK1 | |
| SCHEMBL7452812 | 0.85 | ADORA2A (0.59) | ADORA2AADORA3ADORA2BADORA1PGK1 | |
| Trifluoroacetic Acid SCHEMBL7210014 | 0.84 | ADORA2A (0.57) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7103693 | 0.84 | ADORA2A (0.61) | ADORA2AADORA3ADORA2BADORA1PGK1 | |
| SCHEMBL7115795 | 0.84 | ADORA2A (0.58) | ADORA2AADORA3ADORA2BADORA1PGK1 | |
| SCHEMBL7103326 | 0.84 | ADORA2A (0.59) | ADORA2AADORA3ADORA2BADORA1PGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056759-A1 | 2-(PURIN-9-YL) -TETRAHYDROFURAN-3, 4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999041267-A1 | 2-(PURIN-9-YL) -TETRAHYDROFURAN-3, 4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-08-19 | — | — | WO | disclosed |