Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.79 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.40 |
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081029 | 0.92 | F2 (0.81) | F2ITGB3ITGA2BF10PLAT | |
| Ximelagatran SCHEMBL15908919 | 0.88 | F2 (1.00) | F2ITGB3ITGA2BF10PLAT | |
| Ximelagatran SCHEMBL14509860 | 0.88 | F2 (1.00) | F2ITGB3ITGA2BF10PLAT | |
| Ximelagatran SCHEMBL19065093 | 0.88 | F2 (1.00) | F2ITGB3ITGA2BF10PLAT | |
| Ximelagatran SCHEMBL4845 | 0.88 | F2 (1.00) | F2ITGB3ITGA2BF10PLAT | |
| SCHEMBL8075938 | 0.83 | F2 (0.68) | F2ITGB3ITGA2BF10PLAT | |
| SCHEMBL8080981 | 0.83 | F2 (0.67) | F2ITGB3ITGA2BF10PLAT | |
| Ximelagatran SCHEMBL7222774 | 0.83 | F2 (0.88) | F2ITGB3ITGA2BF10PLAT | |
| SCHEMBL15908918 | 0.82 | F2 (0.73) | F2ITGB3ITGA2BF10PLAT | |
| SCHEMBL17473611 | 0.82 | F2 (0.73) | F2ITGB3ITGA2BF10PLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009018807-A9 | OXAZOLIDINONES AS FACTOR XA INHIBITORS, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF IN THERAPY | SCHEBO BIOTECH AG (DE) | 2009-11-12 | — | — | WO | disclosed |
| WO-2009018807-A1 | NOVEL PHARMACEUTICALS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF IN THERAPY | SCHEBO BIOTECH AG (DE) | 2009-02-12 | — | — | WO | disclosed |