Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.52 |
| ▸ | FNTA | P49354 | 12/20 | 0.48 |
| ▸ | FNTB | P49356 | 12/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 12/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.46 |
| ▸ | ERG | P11308 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8531991 | 1.00 | CYP11B1 (0.52) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8096859 | 0.87 | CYP11B1 (0.51) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8097503 | 0.87 | CYP11B1 (0.51) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL14420575 | 0.87 | CYP11B1 (0.51) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8534856 | 0.85 | CYP11B1 (0.49) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8097403 | 0.85 | CYP11B1 (0.49) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8103727 | 0.84 | FNTA (0.55) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8441677 | 0.84 | FNTA (0.55) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8417257 | 0.83 | FNTA (0.52) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8088808 | 0.83 | CYP11B1 (0.44) | CYP11B1CYP11B2FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |
| US-5817678-A | IMIDAZOLE-CONTAINING PIPERIDINE DERIVATIVES, PEPTIDEMIMETIC | MERCK & CO., INC. (US) | 1998-10-06 | — | — | US | disclosed |