Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663599 | 0.92 | SMN1; SMN2 (0.36) | TSHRNPC1TP53MAPTNFKB1 | |
| SCHEMBL8090258 | 0.90 | CA12 (0.40) | MAPTSMN1; SMN2MEN1KMT2ACA12 | |
| SCHEMBL8604446 | 0.89 | TP53 (0.39) | TSHRNPC1TP53MAPTNFKB1 | |
| SCHEMBL8604039 | 0.89 | TSHR (0.39) | TSHRNPC1TP53MAPTNFKB1 | |
| SCHEMBL8607080 | 0.87 | NOTUM (0.40) | NOTUM | |
| SCHEMBL8103747 | 0.81 | MCHR1 (0.48) | TSHRNPC1TP53MAPTNFKB1 | |
| SCHEMBL2053916 | 0.79 | MEN1 (0.38) | TSHRNPC1TP53MAPTNFKB1 | |
| SCHEMBL8096830 | 0.78 | MCHR1 (0.44) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL8099260 | 0.78 | MEN1 (0.38) | TSHRNPC1TP53MAPTNFKB1 | |
| SCHEMBL8098995 | 0.78 | CA12 (0.38) | TSHRNPC1TP53MAPTNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022976-A | Process for the production of 5-hydroxyoxazolidinones | ZENECA LIMITED | 2000-02-08 | — | — | US | disclosed |
| EP-0828720-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 5-HYDROXY-OXAZOLIDIN-4-ONE | ZENECA LIMITED (GB) | 1998-03-18 | — | — | EP | disclosed |
| US-5688962-A | Cyclization process for making oxazolikinones | ZENECA LIMITED (GB) | 1997-11-18 | — | — | US | disclosed |
| EP-0763020-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1996037483-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 5-HYDROXY-OXAZOLIDIN-4-ONE | ZENECA LIMITED (GB) | 1996-11-28 | — | — | WO | disclosed |
| WO-1995033719-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |