Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.81 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4409616 | 0.90 | CNR2 (1.00) | CNR2ALDH1A1 | |
| SCHEMBL4411949 | 0.90 | CNR2 (0.82) | CNR2TP53MDM2 | |
| SCHEMBL4409562 | 0.89 | CNR2 (0.84) | CNR2ALDH1A1TP53 | |
| SCHEMBL4418089 | 0.88 | CNR2 (0.82) | CNR2ALDH1A1 | |
| SCHEMBL7029384 | 0.88 | CNR2 (0.79) | CNR2 | |
| SCHEMBL4417635 | 0.87 | CNR2 (0.77) | CNR2 | |
| SCHEMBL4414334 | 0.86 | CNR2 (0.79) | CNR2ALDH1A1 | |
| SCHEMBL4417012 | 0.86 | CNR2 (0.79) | CNR2 | |
| SCHEMBL6363703 | 0.85 | CNR2 (0.77) | CNR2ALDH1A1TP53 | |
| SCHEMBL4405983 | 0.80 | CNR2 (1.00) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |