Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061470 | 0.85 | MAOB (0.57) | MAOBSIGMAR1 | |
| SCHEMBL11061464 | 0.85 | MAOB (0.57) | MAOBSIGMAR1 | |
| SCHEMBL10479465 | 0.83 | MAOB (0.56) | MAOBSIGMAR1 | |
| SCHEMBL10479468 | 0.83 | MAOB (0.56) | MAOBSIGMAR1 | |
| SCHEMBL13226039 | 0.81 | MAOB (0.53) | MAOBSIGMAR1 | |
| SCHEMBL10717190 | 0.81 | MAOB (0.53) | MAOBSIGMAR1 | |
| Alcohol SCHEMBL2947640 | 0.80 | IDO1 (0.54) | IDO1ALDH1A1 | |
| SCHEMBL4181089 | 0.80 | IDO1 (0.58) | IDO1ALDH1A1 | |
| SCHEMBL27329 | 0.80 | IDO1 (0.58) | IDO1ALDH1A1 | |
| SCHEMBL9338782 | 0.78 | CYP2C9 (0.60) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |