Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | KIF11 | P52732 | 2/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL559143 | 0.82 | MTOR (0.39) | NOTUMSMN1; SMN2TP53PKMNPC1 | |
| SCHEMBL22261807 | 0.78 | CCNB2 (0.37) | MAPTLMNANOTUMPKMCYP1A2 | |
| SCHEMBL22261804 | 0.78 | NISCH (0.42) | MAPTLMNANOTUMSMN1; SMN2TP53 | |
| SCHEMBL22261806 | 0.78 | CCNB2 (0.37) | MAPTNOTUMNPC1RAB9AMAPK14 | |
| SCHEMBL6131642 | 0.76 | CYP2A6 (0.35) | — | |
| SCHEMBL22261802 | 0.74 | CLK4 (0.48) | MAPTSMN1; SMN2TP53PKMKDM4E | |
| SCHEMBL15662921 | 0.72 | HSP90AA1 (0.35) | CYP2D6MAPK14 | |
| SCHEMBL21796358 | 0.70 | CYP11B1 (0.42) | NOTUMKDM4ENPC1RAB9A | |
| SCHEMBL7500881 | 0.69 | CYP17A1 (0.42) | MAPTNOTUMCYP3A4KDM4E | |
| SCHEMBL9955444 | 0.69 | NISCH (0.40) | SMN1; SMN2NPC1RAB9AMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063956-A | APPLYING FUNGICIDE OR INSECTICIDE TO THE LOCUS WHERE CONTROL IS DESIRED | ROHM AND HAAS COMPANY (US) | 2000-05-16 | — | — | US | disclosed |