⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333198 | 0.70 | — | — | |
| SCHEMBL9447794 | 0.69 | — | — | |
| SCHEMBL7350093 | 0.61 | — | — | |
| SCHEMBL3937999 | 0.60 | — | — | |
| SCHEMBL3932417 | 0.58 | — | — | |
| SCHEMBL8121239 | 0.57 | — | — | |
| SCHEMBL10859312 | 0.55 | — | — | |
| SCHEMBL2045014 | 0.50 | — | — | |
| SCHEMBL4500205 | 0.46 | — | — | |
| SCHEMBL3537152 | 0.46 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747393-B1 | Thiazolo benzazepine containing dual action inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2000-11-08 | — | — | EP | disclosed |
| EP-0747393-A1 | Thiazolo benzazepine containing dual action inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |