Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 14/20 | 0.51 |
| ▸ | GRIA2 | P42262 | 14/20 | 0.51 |
| ▸ | GRIA3 | P42263 | 14/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 14/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 8/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 8/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 8/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 8/20 | 0.41 |
| ▸ | GRIK4 | Q16099 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083806 | 0.94 | GRIA1 (0.49) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8098793 | 0.81 | GRIA1 (0.53) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8083730 | 0.80 | GRIA1 (0.52) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8095672 | 0.80 | GRIA1 (0.51) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8091804 | 0.78 | GRIA1 (0.49) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8083798 | 0.78 | GRIA1 (0.52) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8090247 | 0.77 | GRIA1 (0.47) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8090724 | 0.77 | GRIA1 (0.47) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8083572 | 0.77 | GRIA1 (0.50) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8095918 | 0.76 | GRIA1 (0.47) | GRIA1GRIA2GRIA3GRIA4GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136805-A | Quinoxaline dione derivatives, their production and their use in medicaments | SCNERING AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |