SCHEMBL8091142

SCHEMBL8091142

O=c1c2ccccc2sc2cccc(Oc3cccc4sc5ccccc5c(=O)c34)c12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.56
NPC1 O15118 4/20 0.56
RAB9A P51151 4/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2C9 P11712 1/20 0.56
HPGD P15428 1/20 0.56
CYP2C19 P33261 1/20 0.56
MAOA P21397 2/20 0.49
MAOB P27338 1/20 0.49
KMT2A Q03164 5/20 0.46
MEN1 O00255 4/20 0.46
POLB P06746 3/20 0.45
ALDH1A1 P00352 2/20 0.45
GAA P10253 1/20 0.45
TDP1 Q9NUW8 3/20 0.45
KDM4E B2RXH2 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
GPR3 P46089 1/20 0.45
BLM P54132 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3416670 0.91 NPC1 (0.49) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL29731425 0.90 NPC1 (0.51) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL51305 0.90 NPC1 (0.51) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL30925001 0.86 NPC1 (0.70) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL2789108 0.86 NPC1 (0.70) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL28901490 0.86 MAPT (0.48) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL6688700 0.83 NPC1 (0.51) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL8096279 0.83 MAPT (0.51) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL7098554 0.82 MAPT (0.50) MAPTNPC1RAB9ACYP1A2CYP3A4
SCHEMBL27636034 0.82 MAPT (0.54) MAPTNPC1RAB9ACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104936626-A Coating for substrate GORE & ASS 2015-09-23 CN disclosed
US-6025408-A Liquid thioxanthone photoinitiators FIRST CHEMICAL CORPORATION (US) 2000-02-15 US disclosed
WO-1998042697-A2 LIQUID THIOXANTHONE PHOTOINITIATORS FIRST CHEMICAL CORPORATION (US) 1998-10-01 WO disclosed