Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.51 |
| ▸ | CNR1 | P21554 | 11/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473784 | 0.98 | CNR2 (0.49) | CNR2CNR1PLA2G4BPTPN11NPC1 | |
| SCHEMBL19658037 | 0.88 | POLB (0.50) | NPC1POLBCYP2C9RAB9A | |
| SCHEMBL9116159 | 0.84 | SCN5A (0.50) | PLA2G4BPTPN11 | |
| SCHEMBL10551878 | 0.83 | PLA2G4B (0.42) | PLA2G4BPTPN11NPC1POLBCYP2C9 | |
| SCHEMBL5486023 | 0.81 | TP53 (0.53) | CNR2CNR1PLA2G4B | |
| SCHEMBL120251 | 0.81 | NPC1 (0.64) | NPC1POLBCYP2C9RAB9A | |
| SCHEMBL448815 | 0.80 | RARB (0.50) | CNR2PLA2G4B | |
| SCHEMBL10883390 | 0.79 | KMT2A (0.45) | PLA2G4BPTPN11NPC1POLBCYP2C9 | |
| Isophthalic Acid SCHEMBL11324134 | 0.79 | KMT2A (0.58) | PLA2G4BPTPN11 | |
| SCHEMBL10922725 | 0.78 | CNR2 (0.59) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |