Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.33 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.33 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3744007 | 0.86 | CHRM1 (0.46) | CHRM1CHRM2 | |
| SCHEMBL2918243 | 0.83 | CHRM2 (0.56) | CHRM1CHRM2CHRM3SMN1; SMN2 | |
| SCHEMBL13698869 | 0.78 | CHRM1 (0.40) | CHRM1GRM5CHRM2CHRM3RECQL | |
| SCHEMBL5636057 | 0.78 | CHRM1 (0.56) | CHRM1GRM5CHRM2CHRM3RECQL | |
| SCHEMBL4173985 | 0.78 | CHRM3 (0.42) | CHRM1CHRM2CHRM3ALDH1A1POLB | |
| SCHEMBL4173981 | 0.78 | CHRM3 (0.42) | CHRM1CHRM2CHRM3ALDH1A1POLB | |
| SCHEMBL12518182 | 0.77 | GRM5 (0.42) | CHRM1GRM5CHRM2CHRM3ALDH1A1 | |
| SCHEMBL5454179 | 0.76 | CHRM2 (0.64) | CHRM1CHRM2CHRM3ALDH1A1POLB | |
| SCHEMBL7904414 | 0.76 | CHRM2 (0.64) | CHRM1CHRM2CHRM3ALDH1A1POLB | |
| SCHEMBL18686672 | 0.76 | CHRM2 (0.64) | CHRM1CHRM2CHRM3ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037719-A1 | NOVEL COMPOUNDS AS DIPEPTIDYL PEPTIDASE IV (DPP IV) INHIBITORS | LUPIN LIMITED (IN) | 2009-03-26 | — | — | WO | disclosed |