Tetraethylene Glycol

Tetraethylene Glycol

SCHEMBL8091262

CCCCOC(C)COC(C)COC(C)COC(C)CO.OCCOCCOCCOCCO

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
THRB P10828 1/20 0.47
HTT P42858 1/20 0.47
MAPT P10636 1/20 0.47
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 3/20 0.37
USP2 O75604 2/20 0.37
MAPK1 P28482 2/20 0.37
CYP3A4 P08684 2/20 0.37
LMNA P02545 1/20 0.37
CASP1 P29466 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
SLCO1B3 Q9NPD5 1/20 0.37
SLCO1B1 Q9Y6L6 1/20 0.37
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27395209 0.98 TSHR (0.55) TSHRMEN1KMT2ATHRBHTT
Di(Hydroxyethyl)Ether SCHEMBL6226123 0.98 TSHR (0.53) TSHRMEN1KMT2ATHRBHTT
SCHEMBL8707531 0.94 TSHR (0.53) TSHRMEN1KMT2ATHRBHTT
SCHEMBL27702275 0.93 TSHR (0.49) TSHRMEN1KMT2ATHRBHTT
SCHEMBL28824140 0.91 TSHR (0.47) TSHRMEN1KMT2ATHRBHTT
Di(Hydroxyethyl)Ether SCHEMBL16610460 0.91 TSHR (0.61) TSHRMEN1KMT2ATHRBHTT
Ethylene Glycol SCHEMBL5926093 0.90 TDP1 (0.40) TSHRMEN1KMT2ATHRBHTT
Butoxyethanol SCHEMBL25266385 0.90 TSHR (0.65) TSHRMEN1KMT2ATHRBHTT
SCHEMBL11133571 0.89 TDP1 (0.42) TSHRTDP1ALDH1A1USP2LMNA
SCHEMBL15375 0.89 TDP1 (0.42) TSHRTDP1ALDH1A1USP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0725043-B1 Cement dispersing agent MBT HOLDING AG (CH) 2000-10-18 EP claimed
EP-0725043-B1 Cement dispersing agent MBT HOLDING AG (CH) 2000-10-18 EP disclosed
US-5660626-A CARBOXYLIC ACID POLYMERS HAVING GRAFTED SIDE CHAINS OF ALKYLENE GLYCOL OLIGOMERS, POLYALCOHOLS OR POLYOXYALKYLENE GLYCOLS AS SHRINKAGE REDUCING DISPERSANTS CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 1997-08-26 US disclosed
EP-0725043-A2 Cement dispersing agent SANDOZ LTD. (CH) 1996-08-07 EP disclosed