SCHEMBL8091296

SCHEMBL8091296

C#CO.C#CO.NC(=O)CCCCC(N)=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.39
CYP1A2 P05177 3/20 0.39
CYP2C19 P33261 3/20 0.39
SOAT1 P35610 2/20 0.39
TP53 P04637 2/20 0.39
CYP3A4 P08684 2/20 0.39
MEN1 O00255 2/20 0.39
FAAH O00519 1/20 0.39
CYP2D6 P10635 3/20 0.39
CYP2C9 P11712 2/20 0.39
HSD17B10 Q99714 2/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 3/20 0.35
LMNA P02545 5/20 0.35
PMP22 Q01453 3/20 0.35
ALOX15 P16050 3/20 0.35
BLM P54132 3/20 0.35
ALDH1A1 P00352 2/20 0.35
RECQL P46063 2/20 0.35
GMNN O75496 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL125606 0.83 KMT2A (0.48) KMT2ACYP1A2CYP2C19SOAT1TP53
SCHEMBL15124812 0.80
SCHEMBL699936 0.79 KMT2A (0.52) KMT2ACYP1A2CYP2C19SOAT1TP53
SCHEMBL252458 0.79 KMT2A (0.46) KMT2ACYP1A2CYP2C19SOAT1TP53
SCHEMBL14760174 0.79 KMT2A (0.52) KMT2ACYP1A2CYP2C19SOAT1TP53
SCHEMBL25288050 0.79 KMT2A (0.52) KMT2ACYP1A2CYP2C19SOAT1TP53
SCHEMBL15007818 0.79 KMT2A (0.52) KMT2ACYP1A2CYP2C19SOAT1TP53
SCHEMBL25293705 0.79 KMT2A (0.52) KMT2ACYP1A2CYP2C19SOAT1TP53
SCHEMBL42735 0.79 KMT2A (0.52) KMT2ACYP1A2CYP2C19SOAT1TP53
SCHEMBL25293609 0.79 KMT2A (0.52) KMT2ACYP1A2CYP2C19SOAT1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6051172-A PRODUCING AN EXTRUDED MONOFILAMENT PLASTIC LINE, COOLING THE SURFACE OF THE EXTRUDED MONOFILAMENT PLASTIC LINE, SUPPLYING THE SURFACE-COOLED MONOFILAMENT PLASTIC LINE THROUGH AN ELONGATED STRAIGHT GUIDE, CUTTING Phillips, Robert L. (US) 2000-04-18 US disclosed
US-5941051-A Package & method of manufacture for flexible cutting line Phillips, Robert (US) 1999-08-24 US disclosed
US-5871091-A Package and method of manufacture for flexible cutting line Phillips, Robert L. (US) 1999-02-16 US disclosed