SCHEMBL8091370

SCHEMBL8091370

CCS(=O)(=O)c1ccc(O)c(/N=N/c2c(O)ccc3ccccc23)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.59
CYP2C9 P11712 1/20 0.59
TSHR P16473 1/20 0.59
PTPRA P18433 1/20 0.59
PTPRB P23467 1/20 0.59
CYP2C19 P33261 1/20 0.59
HIF1A Q16665 1/20 0.59
RAPGEF4 Q8WZA2 1/20 0.59
HSD17B10 Q99714 1/20 0.59
MAPT P10636 9/20 0.56
KMT2A Q03164 6/20 0.56
MEN1 O00255 5/20 0.56
THRB P10828 4/20 0.53
MPL P40238 3/20 0.53
CTRC Q99895 2/20 0.53
TDP1 Q9NUW8 6/20 0.53
MAPK1 P28482 5/20 0.53
GAA P10253 3/20 0.53
GLO1 Q04760 2/20 0.53
KDM4E B2RXH2 5/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8091372 1.00 CYP1A2 (0.59) CYP1A2CYP2C9TSHRPTPRAPTPRB
SCHEMBL11021721 0.87 CYP1A2 (0.61) CYP1A2CYP2C9TSHRPTPRAPTPRB
SCHEMBL11021722 0.87 CYP1A2 (0.61) CYP1A2CYP2C9TSHRPTPRAPTPRB
SCHEMBL3003884 0.86 CYP1A2 (0.77) CYP1A2CYP2C9TSHRPTPRAPTPRB
SCHEMBL3003885 0.86 CYP1A2 (0.77) CYP1A2CYP2C9TSHRPTPRAPTPRB
SCHEMBL10875905 0.86 MAPT (0.71) CYP1A2CYP2C9TSHRPTPRAPTPRB
SCHEMBL10875911 0.86 MAPT (0.71) CYP1A2CYP2C9TSHRPTPRAPTPRB
SCHEMBL3797839 0.85 CYP1A2 (0.76) CYP1A2CYP2C9TSHRPTPRAPTPRB
SCHEMBL2304219 0.85 CYP1A2 (0.76) CYP1A2CYP2C9TSHRPTPRAPTPRB
SCHEMBL2304218 0.85 CYP1A2 (0.61) CYP1A2CYP2C9TSHRPTPRAPTPRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6025105-A ELECTROGRAPHIC TONERS WITH BINDER RESINS TOSHIBA AMERICA BUSINESS SOLUTIONS, INC. (US) 2000-02-15 US disclosed