SCHEMBL8091775

SCHEMBL8091775

CCCCCCCCCCCCC(CCCCCCCCCC)COCC(O)CCl

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.44
LMNA P02545 1/20 0.44
HTT P42858 1/20 0.43
LPAR5 Q9H1C0 1/20 0.38
GPR84 Q9NQS5 8/20 0.38
FFAR1 O14842 2/20 0.37
FFAR4 Q5NUL3 1/20 0.37
SPHK1 Q9NYA1 1/20 0.36
CYP3A4 P08684 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36
PRSS1 P07477 1/20 0.35
PRSS2 P07478 1/20 0.35
PRSS3 P35030 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8078612 1.00 USP2 (0.44) USP2LMNAHTTLPAR5GPR84
SCHEMBL171062 0.95 USP2 (0.40) USP2LMNAHTTLPAR5GPR84
SCHEMBL1202052 0.86 CYP3A4 (0.50) USP2LMNAHTTCYP3A4
SCHEMBL15258040 0.85 USP2 (0.47) USP2LMNAHTTLPAR5GPR84
SCHEMBL15258041 0.85 USP2 (0.47) USP2LMNAHTTLPAR5GPR84
SCHEMBL6225681 0.84 USP2 (0.65) USP2LMNAHTTLPAR5GPR84
SCHEMBL6664880 0.84 USP2 (0.65) USP2LMNAHTTLPAR5GPR84
SCHEMBL2878051 0.84 USP2 (0.65) USP2LMNAHTTLPAR5GPR84
SCHEMBL15435147 0.84 USP2 (0.65) USP2LMNAHTTLPAR5GPR84
SCHEMBL10799760 0.84 USP2 (0.65) USP2LMNAHTTLPAR5GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6017547-A GOOD SOLUBILITY, IN PARTICULAR IN THE CONVENTIONAL SOLVENTS USED IN COSMETICS, SUCH AS LOW ALCOHOLS, FATTY SUBSTANCES AND THE USUAL OILS; AMPHIPHILIC CHARACTER, PROPERTIES AND COMPATIBILITY WITH THE SOLVENTS; HOMOGENEITY, STABILITY L'OREAL (FR) 2000-01-25 US disclosed
EP-0652865-B1 HYDROFLUOROCARBON-CONTAINING COMPOUNDS AND THEIR USE IN COSMETIC COMPOSITIONS OREAL (FR) 1997-03-12 EP disclosed
EP-0652865-A1 HYDROFLUOROCARBON-CONTAINING COMPOUNDS AND THEIR USE IN COSMETIC COMPOSITIONS. OREAL (FR) 1995-05-17 EP disclosed
WO-1994027960-A1 HYDROFLUOROCARBON-CONTAINING COMPOUNDS AND THEIR USE IN COSMETIC COMPOSITIONS L'OREAL (FR) 1994-12-08 WO disclosed