Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 8/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7128645 | 0.95 | NPC1 (0.40) | RARBRARANPC1LMNANFKB1 | |
| SCHEMBL7132104 | 0.95 | NPC1 (0.40) | RARBRARANPC1LMNANFKB1 | |
| SCHEMBL7132407 | 0.95 | NPC1 (0.40) | RARBRARANPC1LMNANFKB1 | |
| SCHEMBL7132098 | 0.95 | NPC1 (0.40) | RARBRARANPC1LMNANFKB1 | |
| SCHEMBL7128646 | 0.95 | NPC1 (0.40) | RARBRARANPC1LMNANFKB1 | |
| SCHEMBL7132412 | 0.95 | NPC1 (0.40) | RARBRARANPC1LMNANFKB1 | |
| SCHEMBL7132551 | 0.91 | TSHR (0.39) | RARBRARANPC1LMNANFKB1 | |
| SCHEMBL7126417 | 0.91 | TSHR (0.39) | RARBRARANPC1LMNANFKB1 | |
| SCHEMBL7132762 | 0.91 | TSHR (0.39) | RARBRARANPC1LMNANFKB1 | |
| SCHEMBL7131557 | 0.85 | RARB (0.37) | RARBRARANPC1LMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060226-A1 | LIQUID CRYSTAL POLYMER DEVICES AND MATERIALS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999043763-A1 | LIQUID CRYSTAL POLYMER DEVICES AND MATERIALS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1999-09-02 | — | — | WO | disclosed |