Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543346 | 0.95 | EDNRA (0.74) | EDNRAEDNRB | |
| SCHEMBL7531940 | 0.95 | EDNRA (0.74) | EDNRAEDNRB | |
| SCHEMBL7667519 | 0.94 | EDNRA (0.88) | EDNRAEDNRB | |
| SCHEMBL6960833 | 0.93 | EDNRA (0.87) | EDNRAEDNRB | |
| SCHEMBL6960843 | 0.93 | EDNRA (0.87) | EDNRAEDNRB | |
| SCHEMBL6960837 | 0.92 | EDNRA (0.75) | EDNRAEDNRB | |
| SCHEMBL8008619 | 0.91 | EDNRA (0.86) | EDNRAEDNRB | |
| SCHEMBL8621713 | 0.91 | EDNRA (0.86) | EDNRAEDNRB | |
| SCHEMBL8091942 | 0.91 | EDNRA (0.86) | EDNRAEDNRB | |
| SCHEMBL7945618 | 0.91 | EDNRA (0.73) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162932-A | Stereoselective synthesis of endothelin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-12-19 | — | — | US | disclosed |
| US-6080862-A | PREPARING (1S, 2R, 3S)-3-(2-HYDROXYETH-1-YLOXY)-4-METHOXYPHENYL) 1-(3,4-METHYLENEDIOXYPHENYL) 5-(PROP-1-YLOXY)INDANE-2-CARBOXYLIC ACID | SMITHKLINE BEECHAM CORPORATION (US) | 2000-06-27 | — | — | US | disclosed |