Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 15/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | PDE5A | O76074 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1063103 | 0.82 | ABCG2 (1.00) | ABCG2MEN1KMT2APDE5AMAPT | |
| SCHEMBL13945461 | 0.81 | MEN1 (0.97) | ABCG2MEN1KMT2APDE5AMAPT | |
| SCHEMBL5104228 | 0.80 | ABCG2 (1.00) | ABCG2MEN1KMT2APDE5AMAPT | |
| SCHEMBL1058652 | 0.80 | ABCG2 (1.00) | ABCG2MEN1KMT2APDE5AMAPT | |
| SCHEMBL27066418 | 0.79 | ABCG2 (0.72) | ABCG2MEN1KMT2APDE5AMAPT | |
| SCHEMBL1083771 | 0.79 | MEN1 (0.98) | ABCG2MEN1KMT2APDE5AMAPT | |
| SCHEMBL5104461 | 0.78 | ABCG2 (0.79) | ABCG2MEN1KMT2APDE5AMAPT | |
| SCHEMBL13969181 | 0.78 | ABCG2 (0.76) | ABCG2MEN1KMT2APDE5AMAPT | |
| SCHEMBL1063481 | 0.77 | ABCG2 (1.00) | ABCG2MEN1KMT2APDE5AMAPT | |
| SCHEMBL1063549 | 0.77 | ABCG2 (1.00) | ABCG2MEN1KMT2AMAPTABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000085-A1 | QUINOLINE AND QUINAZOLINE DERIVATIVES USEFUL AS MODULATORS OF GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2008-12-31 | — | — | WO | disclosed |