SCHEMBL8092153

SCHEMBL8092153

CCC[Si@H]1CC[C@H](CCc2ccc(-c3ccc(F)cc3)cc2)CC1

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.43
MAOA P21397 1/20 0.37
GPR84 Q9NQS5 1/20 0.33
TAAR1 Q96RJ0 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8092154 1.00 MAOB (0.43) MAOBMAOAGPR84TAAR1
SCHEMBL8005590 0.93 MAOB (0.38) MAOBMAOAGPR84
SCHEMBL8005593 0.93 MAOB (0.38) MAOBMAOAGPR84
SCHEMBL8015048 0.92 MAOB (0.40) MAOBMAOAGPR84
SCHEMBL8015052 0.92 MAOB (0.40) MAOBMAOAGPR84
SCHEMBL8015049 0.92 MAOB (0.40) MAOBMAOAGPR84
SCHEMBL7771579 0.91 MAOB (0.40) MAOBMAOA
SCHEMBL7771574 0.91 MAOB (0.40) MAOBMAOA
SCHEMBL7771048 0.88 MAOB (0.43) MAOBMAOA
SCHEMBL8083851 0.88 MAOB (0.38) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7278158-A None JP disclosed
EP-0668286-B1 A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it SHINETSU CHEMICAL CO (JP) 2000-12-20 EP disclosed
US-5523440-A Silacyclohexane compound, a method of preparaing it and a liquid crystal composition containing it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-06-04 US disclosed
JP-H07278158-A SILACYCLOHEXANE COMPOUND, ITS PRODUCTION AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME SHIN ETSU CHEM CO LTD 1995-10-24 JP disclosed
EP-0668286-A1 A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it Shin-Etsu Chemical Co., Ltd. (JP) 1995-08-23 EP disclosed