Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723516 | 0.85 | TSHR (0.68) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL22554415 | 0.83 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDPOLB | |
| SCHEMBL22554411 | 0.83 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDPOLB | |
| SCHEMBL22554416 | 0.83 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDPOLB | |
| SCHEMBL22554418 | 0.83 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDPOLB | |
| SCHEMBL22554425 | 0.83 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDPOLB | |
| SCHEMBL22554403 | 0.83 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDPOLB | |
| SCHEMBL22554417 | 0.83 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDPOLB | |
| SCHEMBL22554408 | 0.83 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDPOLB | |
| SCHEMBL22554412 | 0.83 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051454-A1 | LIQUID-CRYSTALLINE PHOTOCROSSLINKABLE MIXTURE | Rolic AG (CH) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037735-A1 | LIQUID-CRYSTALLINE PHOTOCROSSLINKABLE MIXTURE | ROLIC AG (CH) | 1999-07-29 | — | — | WO | disclosed |