Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | TXN | P10599 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20305800 | 0.81 | CHRNA7 (0.47) | CHRNA7KMT2AMEN1TXNALDH1A1 | |
| SCHEMBL5637621 | 0.75 | KMT2A (0.73) | KMT2AMEN1TXNALDH1A1SMN1; SMN2 | |
| SCHEMBL30702394 | 0.73 | KMT2A (0.71) | KMT2AMEN1TXNALDH1A1HPGD | |
| SCHEMBL28919884 | 0.73 | KMT2A (0.71) | KMT2AMEN1TXNALDH1A1HPGD | |
| SCHEMBL816962 | 0.73 | KMT2A (0.71) | KMT2AMEN1TXNALDH1A1HPGD | |
| SCHEMBL1744058 | 0.72 | KMT2A (0.73) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL9533470 | 0.71 | KMT2A (0.77) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL16727581 | 0.70 | KMT2A (0.49) | CHRNA7KMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL18334796 | 0.70 | KMT2A (0.60) | KMT2AMEN1TXNALDH1A1HPGD | |
| SCHEMBL27969818 | 0.70 | KMT2A (0.52) | CHRNA7KMT2AMEN1TXNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590457-B1 | Benzothiazole derivatives as vulcanisation accelerators suitable for the introduction of polar substituents | BAYER AG (DE) | 2000-12-06 | — | — | EP | disclosed |
| US-6140427-A | 2-(SUBSTITUTED ALKYLTHIO)BENZOTHIAZOLE DERIVATIVES WHICH EFFECT CHAIN TRANSFER OF RUBBER SIDE CHAINS DURING VULCANIZATION | BAYER AG (DE) | 2000-10-31 | — | — | US | disclosed |