Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 20/20 | 0.79 |
| ▸ | MAPK9 | P45984 | 14/20 | 0.79 |
| ▸ | MAPK10 | P53779 | 11/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL849121 | 0.88 | MAPK8 (0.82) | MAPK8MAPK9MAPK10 | |
| SCHEMBL879613 | 0.88 | MAPK8 (1.00) | MAPK8MAPK9MAPK10 | |
| SCHEMBL860430 | 0.88 | MAPK8 (0.81) | MAPK8MAPK9MAPK10 | |
| SCHEMBL879650 | 0.86 | MAPK8 (0.79) | MAPK8MAPK9MAPK10 | |
| SCHEMBL846909 | 0.84 | MAPK8 (0.75) | MAPK8MAPK9MAPK10 | |
| SCHEMBL847901 | 0.83 | MAPK8 (0.73) | MAPK8MAPK9MAPK10 | |
| SCHEMBL849162 | 0.78 | MAPK8 (0.79) | MAPK8MAPK9MAPK10 | |
| SCHEMBL846735 | 0.78 | MAPK8 (0.71) | MAPK8MAPK9MAPK10 | |
| SCHEMBL879581 | 0.78 | MAPK8 (1.00) | MAPK8MAPK9MAPK10 | |
| SCHEMBL847722 | 0.78 | MAPK8 (0.81) | MAPK8MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008138920-A1 | DIHYDROQUINONE AND DIHYDRONAPHTHRIDINE INHIBITORS OF JNK | F. HOFFMANN-LA ROCHE AG (CH) | 2008-11-20 | — | — | WO | disclosed |