SCHEMBL809316

SCHEMBL809316

Nc1cccc(Nc2ccccc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 1.00
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
TDP1 Q9NUW8 3/20 1.00
GAA P10253 3/20 1.00
KDM4E B2RXH2 2/20 1.00
LMNA P02545 2/20 1.00
GFER P55789 1/20 1.00
ALDH1A1 P00352 7/20 0.68
AR P10275 1/20 0.68
CYP3A4 P08684 4/20 0.62
ALOX12 P18054 2/20 0.62
L3MBTL1 Q9Y468 2/20 0.62
HTT P42858 2/20 0.62
CYP1A2 P05177 2/20 0.62
CYP2C9 P11712 2/20 0.62
CYP2C19 P33261 2/20 0.62
HSD17B10 Q99714 3/20 0.57
TSHR P16473 2/20 0.56
NPSR1 Q6W5P4 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29564320 1.00 MAPT (1.00) MAPTMEN1KMT2ATDP1GAA
Hydrochloric Acid SCHEMBL5914585 0.98 MAPT (0.95) MAPTMEN1KMT2ATDP1GAA
SCHEMBL9480199 0.98 MAPT (0.95) MAPTMEN1KMT2ATDP1GAA
Hydrochloric Acid SCHEMBL30855318 0.98 MAPT (0.95) MAPTMEN1KMT2ATDP1GAA
SCHEMBL2127990 0.93 MAPT (0.86) MAPTMEN1KMT2ATDP1GAA
Hydrochloric Acid SCHEMBL21647359 0.90 MAPT (0.82) MAPTMEN1KMT2ATDP1GAA
Hydrochloric Acid SCHEMBL31528395 0.90 MAPT (0.82) MAPTMEN1KMT2ATDP1GAA
SCHEMBL929515 0.88 MAPT (0.79) MAPTMEN1KMT2ATDP1GAA
Acetic Acid SCHEMBL5914600 0.88 MAPT (0.78) MAPTMEN1KMT2ATDP1GAA
SCHEMBL29755970 0.86 MAPT (0.76) MAPTMEN1KMT2ATDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 697 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3873955-B1 AMINO ACID GRAFTED POLYMER WITH SOOT HANDLING PROPERTIES AFTON CHEMICAL CORP (US) 2024-12-04 EP claimed
WO-2024120884-A1 AROMATIC AMINE MODIFIED ACID-OLEFIN COPOLYMER FOR LUBRICANTS BASF SE (DE) 2024-06-13 WO claimed
CN-115639724-B Preparation method and application of photosensitive resin composition 波米科技有限公司 2023-08-08 CN claimed
CN-115650916-A Synthesis method and application of spiro-substituted acridine compound 深圳大学 2023-01-31 CN claimed
CN-115477612-A Synthesis method and application of spiro-substituted acridine compound 深圳大学 2022-12-16 CN claimed
CN-110194984-B Graft polymers with smoke handling properties 雅富顿化学公司 2022-09-23 CN claimed
CN-114874425-A Amino polyether polyol and preparation method thereof 万华化学(宁波)有限公司 2022-08-09 CN claimed
CN-114829556-A Polymeric surfactant compounds 路博润公司 2022-07-29 CN claimed
CN-113166334-B Amino acid grafted polymers with smoke handling properties 雅富顿化学公司 2022-06-21 CN claimed
CN-109705956-B Dispersant viscosity index improvers for enhanced wear protection of engine oils 雅富顿化学公司 2022-05-27 CN claimed
EP-0491456-A1 Dispersant and antioxidant additive TEXACO DEVELOPMENT CORPORATION (US) 1992-06-24 EP claimed
EP-0338672-B1 VISCOSITY INDEX IMPROVER, DISPERSANT AND ANTI-OXIDANT ADDITIVE AND LUBRICATING OIL COMPOSITION CONTAINING SAME TEXACO DEVELOPMENT CORPORATION (US) 1992-06-24 EP claimed
EP-0470698-A1 Oil dispersant and antioxidant additive TEXACO DEVELOPMENT CORPORATION (US) 1992-02-12 EP claimed
EP-0465031-A1 Multifunctional viscosity index improvers TEXACO DEVELOPMENT CORPORATION (US) 1992-01-08 EP claimed
US-5013469-A Butylene-ethylene-styrene polymer reacted with maleic anhydride and aromatic polyamine TEXACO INC. (US) 1991-05-07 US claimed
EP-0414343-A1 VI improver, dispersant, and anti-oxidant additive and lubricating oil composition containing same TEXACO DEVELOPMENT CORPORATION (US) 1991-02-27 EP claimed
US-4900325-A AMINODIPHENYLAMINE COUPLERS, TETRAAMINOPYRIMIDINE DEVELOPERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1990-02-13 US claimed
EP-0338672-A1 Viscosity index improver, dispersant and anti-oxidant additive and lubricating oil composition containing same TEXACO DEVELOPMENT CORPORATION (US) 1989-10-25 EP claimed
US-4863623-A VISCOSITY INDEX, GRAFT POLYMERS OF ETHYLENE MODIFIED WITH AMINE COMPOUND TEXACO INC. (US) 1989-09-05 US claimed
EP-0112537-B1 INCREASE OF THE SPONTANEOUS IGNITION OF ORGANIC DYES AND SUCH DYE PREPARATIONS HOECHST AKTIENGESELLSCHAFT (DE) 1987-04-01 EP claimed