Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | TACR2 | P21452 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094743 | 1.00 | HTR2A (0.60) | HTR2AMAOBS1PR1S1PR2S1PR3 | |
| SCHEMBL8086368 | 1.00 | HTR2A (0.60) | HTR2AMAOBS1PR1S1PR2S1PR3 | |
| SCHEMBL8095312 | 1.00 | HTR2A (0.60) | HTR2AMAOBS1PR1S1PR2S1PR3 | |
| SCHEMBL8095969 | 1.00 | HTR2A (0.60) | HTR2AMAOBS1PR1S1PR2S1PR3 | |
| SCHEMBL8095989 | 1.00 | HTR2A (0.60) | HTR2AMAOBS1PR1S1PR2S1PR3 | |
| SCHEMBL8087470 | 1.00 | HTR2A (0.60) | HTR2AMAOBS1PR1S1PR2S1PR3 | |
| SCHEMBL8100028 | 1.00 | HTR2A (0.60) | HTR2AMAOBS1PR1S1PR2S1PR3 | |
| SCHEMBL8086298 | 1.00 | HTR2A (0.60) | HTR2AMAOBS1PR1S1PR2S1PR3 | |
| SCHEMBL8102592 | 1.00 | HTR2A (0.60) | HTR2AMAOBS1PR1S1PR2S1PR3 | |
| SCHEMBL8086668 | 1.00 | HTR2A (0.60) | HTR2AMAOBS1PR1S1PR2S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |