Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,3-Butanediol SCHEMBL1415145 | 1.00 | TDP1 (0.44) | TDP1SMN1; SMN2TSHRALDH1A1LMNA | |
| 1,5-Pentanediol SCHEMBL6423642 | 0.97 | TSHR (0.43) | TDP1SMN1; SMN2TSHRALDH1A1LMNA | |
| 1,3-Butanediol SCHEMBL28244301 | 0.97 | TSHR (0.43) | TDP1SMN1; SMN2TSHRALDH1A1LMNA | |
| 1,6-Hexanediol SCHEMBL2190350 | 0.97 | TSHR (0.43) | TDP1SMN1; SMN2TSHRALDH1A1LMNA | |
| 1,3-Butanediol SCHEMBL3458713 | 0.94 | TDP1 (0.44) | TDP1SMN1; SMN2TSHRALDH1A1LMNA | |
| 1,3-Butanediol SCHEMBL222874 | 0.90 | — | — | |
| 1,3-Butanediol SCHEMBL3427715 | 0.90 | TDP1 (0.53) | TDP1TSHRALDH1A1LMNATHRB | |
| 1,3-Butanediol SCHEMBL227565 | 0.90 | — | — | |
| 1,3-Butanediol SCHEMBL8176 | 0.90 | — | — | |
| 1,3-Butanediol SCHEMBL9614790 | 0.89 | TSHR (0.43) | TDP1SMN1; SMN2TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061896-A1 | COSMETIC METHOD OF TREATING SKIN | UNILEVER PLC (GB) | 2000-12-27 | — | — | EP | disclosed |
| US-6042841-A | Cosmetic method of treating skin | UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. (US) | 2000-03-28 | — | — | US | disclosed |
| US-6036963-A | COSMETICS FOR SKIN WITH RETINOL, RETINOIC ACID, RETINAL, RETINYL ESTER AND MIXTURES WITH LACTONES AND VEHICLES | CHESEBROUGH-PONDS'S USA CO., DIVISION OF CONOPCO, INC. (US) | 2000-03-14 | — | — | US | disclosed |
| WO-1999055300-A1 | SKIN CARE COSMETIC COMPOSITIONS | UNILEVER PLC (GB) | 1999-11-04 | — | — | WO | disclosed |
| WO-1999047110-A1 | COSMETIC METHOD OF TREATING SKIN | UNILEVER PLC (GB) | 1999-09-23 | — | — | WO | disclosed |