SCHEMBL8093428

SCHEMBL8093428

C/C(=C/C(=O)O)C(=O)O.C=C(C(=O)O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.38
KMT2A Q03164 1/20 0.34
KDM4E B2RXH2 4/20 0.33
MAPT P10636 3/20 0.33
POLB P06746 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
ALDH1A1 P00352 1/20 0.33
PKM P14618 1/20 0.33
CYP2C9 P11712 1/20 0.32
PTGS1 P23219 1/20 0.32
AKR1C3 P42330 1/20 0.32
ATM Q13315 1/20 0.31
TSHR P16473 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8093436 1.00 HTT (0.38) HTTKMT2AKDM4EMAPTPOLB
SCHEMBL27092729 0.90 HTT (0.41) HTTKMT2AKDM4EMAPTPOLB
SCHEMBL27092733 0.90 HTT (0.41) HTTKMT2AKDM4EMAPTPOLB
Methacrylic Acid SCHEMBL1443532 0.87 HTT (0.39) HTTKMT2AKDM4EMAPTPOLB
Ethylene SCHEMBL27652891 0.87 HTT (0.42) HTTKMT2AKDM4EMAPTPOLB
SCHEMBL28517 0.87
SCHEMBL623803 0.87 HTT (0.45) HTTKMT2AKDM4EMAPTPOLB
SCHEMBL5893 0.87
SCHEMBL5894 0.87
SCHEMBL623108 0.87 HTT (0.45) HTTKMT2AKDM4EMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0678573-B1 Process for the manufacture of free-flowing detergent granules PROCTER & GAMBLE (US) 2000-11-29 EP disclosed
EP-0811052-A4 INDUSTRIAL AND INSTITUTIONAL LIQUID CLEANING COMPOSITIONS CONTAINING ALKYL POLYGLYCOSIDE SURFACTANTS HENKEL CORP (US) 1999-10-27 EP disclosed
US-5703037-A NEUTRALIZING ANIONIC SURFACTANT WITH EXCESS ALKALI TO FORM PASTE, MIXING WITH SPRAY DRIED POWDER CONTAINING ANIONIC POLYMER AND CATIONIC SURFACTANT, DRYING GRANULAR PRODUCT THE PROCTER & GAMBLE COMPANY (US) 1997-12-30 US disclosed
EP-0811052-A1 INDUSTRIAL AND INSTITUTIONAL LIQUID CLEANING COMPOSITIONS CONTAINING ALKYL POLYGLYCOSIDE SURFACTANTS HENKEL CORPORATION (US) 1997-12-10 EP disclosed
WO-1996025479-A1 INDUSTRIAL AND INSTITUTIONAL LIQUID CLEANING COMPOSITIONS CONTAINING ALKYL POLYGLYCOSIDE SURFACTANTS HENKEL CORPORATION (US) 1996-08-22 WO disclosed
WO-1995029215-A1 PROCESS FOR THE MANUFACTURE OF FREE-FLOWING DETERGENT GRANULES THE PROCTER & GAMBLE COMPANY (US) 1995-11-02 WO disclosed
EP-0678573-A1 Process for the manufacture of free-flowing detergent granules THE PROCTER & GAMBLE COMPANY (US) 1995-10-25 EP disclosed