Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.52 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8728583 | 0.88 | CHRM2 (0.68) | CHRM2SCN8AL3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL10556589 | 0.77 | CHRM2 (0.81) | CHRM2SCN8AL3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL19509215 | 0.77 | CHRM2 (0.81) | CHRM2SCN8AL3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL11083068 | 0.77 | CHRM2 (0.81) | CHRM2SCN8AL3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL728747 | 0.76 | CYP1A2 (0.65) | CHRM2SCN8AALDH1A1NPSR1CYP1A2 | |
| SCHEMBL2188249 | 0.76 | CHRM2 (0.78) | CHRM2SCN8AL3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL2711100 | 0.72 | CHRM2 (0.75) | CHRM2SCN8AL3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL27299308 | 0.72 | CYP1A2 (0.54) | CHRM2L3MBTL1ALDH1A1NPSR1CYP1A2 | |
| SCHEMBL11594897 | 0.69 | CHRM2 (0.93) | CHRM2SCN8AALDH1A1NPSR1CYP1A2 | |
| SCHEMBL27298367 | 0.69 | CHRM2 (0.69) | CHRM2SCN8AL3MBTL1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973936-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |